Hi Donald,

Can this be done even if I have one condition? 

The other question is can this be done for parametric modulation? 

Regards,

Aser A

On 13 Mar 2014, at 03:15 pm, "MCLAREN, Donald" <[log in to unmask]> wrote:

In your case, with a task-design, the connectivity changes from baseline to task A to task B to .... Thus, the preferred analysis in task data is to look at how the connectivity changes between a seed region and the rest of the brain between the tasks in your experiment.

In my opinion, the best approach for answering the question is to use generalized psychophysiological interactions (gPPI). The method has been compared to PPI in SPM (McLaren et al. 2012) and also SPM PPI and beta-series correlations (Cisler et al. 2013)

Take a look at the gPPI Toolbox (www.nitrc.org/projects/gppi). The toolbox has a test dataset and a tutorial, which should help you implement the toolbox on your system.

Best Regards, Donald McLaren
=================
D.G. McLaren, Ph.D.
Research Fellow, Department of Neurology, Massachusetts General Hospital and
Harvard Medical School
Postdoctoral Research Fellow, GRECC, Bedford VA
Website: http://www.martinos.org/~mclaren
Office: (773) 406-2464
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On Thu, Mar 13, 2014 at 8:55 AM, Aser A <[log in to unmask]> wrote:

Hello,

I am curious about something and have a very naive question:-)

If I have a task ( rapid event design ) and would like to see the influence of one region on another ( or others ) ( OR the functional connectivity between two regions ), how can I do this in a practical terms ? I mean the basic exact steps that I should if the question, actually, does make sense?

Regards

Aser A