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Dear Yuko,
Let’s say you have a negative estimate for a modulatory input A from Region X to Region Y. This would suggest that Region X causes a reduction in the rate of
change of Region Y. This isn’t exactly a negative correlation, but it matches the interpretation you are looking for.
Best,
Peter.
From: SPM (Statistical Parametric Mapping) [mailto:[log in to unmask]]
On Behalf Of Yuko
Sent: 09 March 2014 03:05
To: [log in to unmask]
Subject: [SPM] About DCM design
Dear SPM experts,
I would like to know if I can detect negative correlations between ROIs using DCM.
My hypothesis is that a neural projection from ROI(1) to ROI(2) suppresses neural activity in ROI(2) during condition A.
I would like to test this hypothesis.
Can I test this hypothesis using DCM (or PPI)?
Any suggestion would be highly appreciated.
Many thanks.
Yuko