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Hi Elijah, no they aren't: SIENAr localizes brain edge movements between two time point across subjects while VBM localizes changes / differences in GM "density". The results may overlap but conceptually the two methods are different. Cheers, Andreas Am 17.03.14 11:44 schrieb "Elijah Mak" unter <[log in to unmask]>: >Hi Andreas, > >Thakn you for your response. I was asking about the major differences >between SIENAr voxelwise and longitudinal VBM? I am not sure if my >understanding is correct .. are both techniques are essentially answering >the same question? > >Many thanks. >Best Regards, >Elijah