Highest we had last two years was 795.000 µg/L x 0.86 = 683.700 IU/L No high dose hook was seen on E170 Best regards, Bart B.E.P.B. Ballieux PhD Clinical Biochemist Endocrinology CKCL, E2-P Leiden University Medical Centre P.O.box 9600 2300RC Leiden Tel: +3171-5262165 Fax: +3171-5266753 email: [log in to unmask]<mailto:[log in to unmask]> P Please consider the environment before printing this e-mail Van: Clinical biochemistry discussion list [mailto:[log in to unmask]] Namens Salter Simon (ROYAL FREE LONDON NHS FOUNDATION TRUST) Verzonden: vrijdag 7 maart 2014 12:28 Aan: [log in to unmask] Onderwerp: Roche AFP anaylitcal range Dear Roche users (apologies to everyone else), Has anyone got any validation data for the Roche/Cobas AFP assay regarding its performance above 50,000kU/L which they would not mind sharing? The kit insert says to report anything over that as >50,000 but also says that no high dose hook was noted with concentrations up to 1,000,000kU/L. I am trying to find out high we can confidently go on this assay but it takes a long time to collect samples of this high concentration. We are using the Roche modular E170, so any data from that specific analyser would be greatly appreciated. Many thanks, Simon Salter Clinical Biochemistry, Royal Free Hospital, London ******************************************************************************************************************** This message may contain confidential information. If you are not the intended recipient please inform the sender that you have received the message in error before deleting it. Please do not disclose, copy or distribute information in this e-mail or take any action in reliance on its contents: to do so is strictly prohibited and may be unlawful. Thank you for your co-operation. NHSmail is the secure email and directory service available for all NHS staff in England and Scotland NHSmail is approved for exchanging patient data and other sensitive information with NHSmail and GSi recipients NHSmail provides an email address for your career in the NHS and can be accessed anywhere ******************************************************************************************************************** ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/