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I don't think it's a problem. I've done it once or twice. As long as your subject doesn't have a TBI or stroke or some other major issue, I doubt you would see any difference between the T1's a week apart. You might as well save those 5 minutes for another fMRI run. On 02/05/2014 01:11 PM, Colin Hawco wrote: > Hello all, > > I am planning an imaging study which involves 2 sessions separate by > about a week. In the first session we collect a nice high res > anatomical T1 scan. For the second session, the emphasis is on the > task based fMRI. > > At present I am using my T1 for image registration/normalization. > Hiwever, in the current design, I want to maximize my time in the > scanner and number of trials in fMRI. So I hope to avoid a repeated T1 > scan. > > Is there any issues with using a T1 scvan from an earlier session > (e.g. 1-2 weeks previous) to calculate the normalization parameters (I > am using segmentation for this, as suggested in the SPM8 manual in the > examples)? Will running co-registration on the T1 be sufficient? > > It is worth noting there may be differences in head position and angle > due to the nature of the second scan. > > > Thanks : ) > > Colin > >