Yeah, I figure the T1s will be virtually identical, I am just concerned about getting an accurate registration when I normalize to MNI space. As far as I know it should be OK, but I don't want a reviewer coming after me about it once the study is done. : ) On 5 February 2014 13:01, Chris Watson < [log in to unmask]> wrote: > I don't think it's a problem. I've done it once or twice. As long as > your subject doesn't have a TBI or stroke or some other major issue, I > doubt you would see any difference between the T1's a week apart. You might > as well save those 5 minutes for another fMRI run. > > > On 02/05/2014 01:11 PM, Colin Hawco wrote: > > Hello all, > > I am planning an imaging study which involves 2 sessions separate by > about a week. In the first session we collect a nice high res anatomical T1 > scan. For the second session, the emphasis is on the task based fMRI. > > At present I am using my T1 for image registration/normalization. > Hiwever, in the current design, I want to maximize my time in the scanner > and number of trials in fMRI. So I hope to avoid a repeated T1 scan. > > Is there any issues with using a T1 scvan from an earlier session (e.g. > 1-2 weeks previous) to calculate the normalization parameters (I am using > segmentation for this, as suggested in the SPM8 manual in the examples)? > Will running co-registration on the T1 be sufficient? > > It is worth noting there may be differences in head position and angle > due to the nature of the second scan. > > > Thanks : ) > > Colin > > > >