Hello,
I have a few questions regarding using SPM for
structural MRI.
I have two groups (N=5): control and disease. The brains
are pre-processed and in register with each other, and
have the same dimensions and orientation. Cortical
thickness surface measurements were calculated and these
values stored as intensities in
3D NIfti images in the same space as the
registered brains.
All that is left to do is to run a t-test for each voxel
location
in the thickness data.
I have tried using the t-test in the Second-Level
Analysis under
fMRI statistics for this purpose but it doesn't seem to
work. Specifically, it says "Inner matrix
dimensions must agree" in the Matlab console and I'm pretty confident the
images are the same dimensions.
I am going to "Specify 2nd Level" and entering my groups.
Then, I click "Estimate" and select the "SPM.mat" file. Is
there something else I should be doing instead?
Thank you for your time,
Nadejda Zaharieva
Candidate for M.Sc.
Neuroscience; in progress
B.Sc. Hons
Computational Science, Chemistry