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You can multiply the beta image by the canonical HRF. The canonical HRF is stored in SPM.xBF. If you think the shape of the response varies by task and brain region as the duration of the neural activity is different, then you might want to consider using an FIR model instead of assuming a response. You can also plot the PSTH in SPM. This is described in the manual. Best Regards, Donald McLaren ================= D.G. McLaren, Ph.D. Research Fellow, Department of Neurology, Massachusetts General Hospital and Harvard Medical School Postdoctoral Research Fellow, GRECC, Bedford VA Website: http://www.martinos.org/~mclaren Office: (773) 406-2464 ===================== This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is intended only for the use of the individual or entity named above. If the reader of the e-mail is not the intended recipient or the employee or agent responsible for delivering it to the intended recipient, you are hereby notified that you are in possession of confidential and privileged information. Any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited and may be unlawful. If you have received this e-mail unintentionally, please immediately notify the sender via telephone at (773) 406-2464 or email. On Tue, Dec 17, 2013 at 3:45 PM, Carmen Walter <[log in to unmask]>wrote: > Thank you very much for your answer! > Yes, I assumed the canonical HRF and I am particularly interested in the > amplitude of the HRF at different time points for different voxels. Is > there any way to extract the amplitudes? > Thank you for your help!! > carmen > >