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Hi John,
if you look for evidence based information you need to use or compare NNH as calculated in studies. Studies about ADR are often observational, cohort or case-control studies.
There are big drug ADR databases like eudravigilance (Europe) or FAERS (US): these are based on spontaneous reporting; the problem here is you do not have a good denominator to use and only signals can be detected.
Hope this help.
Felice Musicco
hospital pharmacist at IFO, Rome Italy www.ifo.it
pharmacovigilance service
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Data: 19/01/2014 17.49
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Ogg: Adverse events
Hi All,This is a real long-shot but does anyone know of a resource that quantifies the number and seriousness of a given drug's adverse event profile?In other words if you are choosing between two drugs with a similar efficacy and similar price you might want to compare adverse events. One intervention might have a few minor adverse events while the other intervention might have a few minor adverse events plus 1-2 major adverse events associated with it. So, one might be classed as low risk while the other moderate risk or even high risk.Any ideas?BWjon
--Jon BrasseyTrip DatabaseFind evidence fast