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Can you explain what you've tried? Have you searched the mailing list 
archives?

On 12/20/2013 10:51 AM, Justin Thomas wrote:
> Hi, it’s my first time using SPM for image processing, and I’m having 
> trouble segmenting my nifti file. I’m doing research on Alzheimer's 
> disease, and I was thinking SPM might be a faster way to get rid of 
> the skull in my images. Can anyone help me?
>
> Thanks,
> Justin Thomas
>