Print

Print


Hi Donald,

From which one sample t-tests of these I should create my ROIs: one sample in the summation of all conditions ( slow + mid + fast ) versus force    OR from the one-sample t-test of each level of speed (i.e. slow vs rest, mid vs rest ...etc )

Thanks

Aser


On Mon, Dec 16, 2013 at 4:18 PM, MCLAREN, Donald <[log in to unmask]> wrote:
As you want to do what the previous paper did, you need to create your ROIs from your one-sample t-test. Then, extract the data for each ROI and for each movement speed and use your favourite statistical program (e.g. STATA, SPSS, SAS, etc.) to do the two-way ANOVA of ROI and movement speed.

SPM is not equipped to do a two-way ANOVA between regions.

Best Regards, Donald McLaren
=================
D.G. McLaren, Ph.D.
Research Fellow, Department of Neurology, Massachusetts General Hospital and
Harvard Medical School
Postdoctoral Research Fellow, GRECC, Bedford VA
Website: http://www.martinos.org/~mclaren
Office: (773) 406-2464
=====================
This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED
HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is
intended only for the use of the individual or entity named above. If the
reader of the e-mail is not the intended recipient or the employee or agent
responsible for delivering it to the intended recipient, you are hereby
notified that you are in possession of confidential and privileged
information. Any unauthorized use, disclosure, copying or the taking of any
action in reliance on the contents of this information is strictly
prohibited and may be unlawful. If you have received this e-mail
unintentionally, please immediately notify the sender via telephone at (773)
406-2464 or email.


On Mon, Dec 16, 2013 at 9:48 AM, Aser A <[log in to unmask]> wrote:
Hi all,

I have an experiments that contains three type of movement: slow
movement, mid movement, and fast movement.

How can I see the effects of changing the speed movement on different
brain regions?

For example, what I would like to do is to create 10 ROIs. Then I
would like to see the beta value of these ROIs at each level of
movement. Then I would like to plot this relation. I want to do this
at the group level.

What I have done at the within subject level is the following:

I defined three regressors : slow, mid, and fast.

I then defined four contrast: slow vs rest, mid vs rest, fast vs rest,
and the summation of ( slow + mid + fast ) vs rest.

I thought of the following:

I do a between subject analysis : one sample t test of the summation
contrast, then I defined the ROIs. But here is the missing part for me
how to see the effect of movement speed on these ROIs.

I found a paper that is somehow similar to what I would like to do.
However, they did not use SPM and they used a two way anova.

Keisker, Birgit, et al. "Differential force scaling of fine‐graded
power grip force in the sensorimotor network." Human brain mapping
30.8 (2009): 2453-2465.

I really would like to to get similar approach to what they did and
similar observation or results.

So any advice will be for sure appreciated,

Many thanks,

Aser S