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Hi Donald, From which one sample t-tests of these I should create my ROIs: one sample in the summation of all conditions ( slow + mid + fast ) versus force OR from the one-sample t-test of each level of speed (i.e. slow vs rest, mid vs rest ...etc ) Thanks Aser On Mon, Dec 16, 2013 at 4:18 PM, MCLAREN, Donald <[log in to unmask]>wrote: > As you want to do what the previous paper did, you need to create your > ROIs from your one-sample t-test. Then, extract the data for each ROI and > for each movement speed and use your favourite statistical program (e.g. > STATA, SPSS, SAS, etc.) to do the two-way ANOVA of ROI and movement speed. > > SPM is not equipped to do a two-way ANOVA between regions. > > Best Regards, Donald McLaren > ================= > D.G. McLaren, Ph.D. > Research Fellow, Department of Neurology, Massachusetts General Hospital > and > Harvard Medical School > Postdoctoral Research Fellow, GRECC, Bedford VA > Website: http://www.martinos.org/~mclaren > Office: (773) 406-2464 > ===================== > This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED > HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is > intended only for the use of the individual or entity named above. If the > reader of the e-mail is not the intended recipient or the employee or agent > responsible for delivering it to the intended recipient, you are hereby > notified that you are in possession of confidential and privileged > information. Any unauthorized use, disclosure, copying or the taking of any > action in reliance on the contents of this information is strictly > prohibited and may be unlawful. If you have received this e-mail > unintentionally, please immediately notify the sender via telephone at > (773) > 406-2464 or email. > > > On Mon, Dec 16, 2013 at 9:48 AM, Aser A <[log in to unmask]> wrote: > >> Hi all, >> >> I have an experiments that contains three type of movement: slow >> movement, mid movement, and fast movement. >> >> How can I see the effects of changing the speed movement on different >> brain regions? >> >> For example, what I would like to do is to create 10 ROIs. Then I >> would like to see the beta value of these ROIs at each level of >> movement. Then I would like to plot this relation. I want to do this >> at the group level. >> >> What I have done at the within subject level is the following: >> >> I defined three regressors : slow, mid, and fast. >> >> I then defined four contrast: slow vs rest, mid vs rest, fast vs rest, >> and the summation of ( slow + mid + fast ) vs rest. >> >> I thought of the following: >> >> I do a between subject analysis : one sample t test of the summation >> contrast, then I defined the ROIs. But here is the missing part for me >> how to see the effect of movement speed on these ROIs. >> >> I found a paper that is somehow similar to what I would like to do. >> However, they did not use SPM and they used a two way anova. >> >> Keisker, Birgit, et al. "Differential force scaling of fine‐graded >> power grip force in the sensorimotor network." Human brain mapping >> 30.8 (2009): 2453-2465. >> >> I really would like to to get similar approach to what they did and >> similar observation or results. >> >> So any advice will be for sure appreciated, >> >> Many thanks, >> >> Aser S >> > >