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Hi, It is fine to only use respiration - just set the order of the cardiac and its interactions to zero. You will need to include a dummy trace for the cardiac (just point it at the respiratory trace) if you are using the GUI and then everything should work fine. All the best, Mark On 5 Dec 2013, at 17:36, Tae-Ho Lee <[log in to unmask]> wrote: > Hi all, > > I'm currently trying to do get brain stem signal with FSL's PNM toolbox. So far I could successfully generate PNM regressors with ECG and respiration data and model it. Unfortunately, one participant's ECG data was severely contaminated by the scanner noise, so the respiration data is the only physio data that I can use for PNM. Given the situation, I wonder whether I can generate physio regressor in PNM only with respiration data or not. Otherwise, is it okay to put time series raw respiration data into the design matrix instead of using PNM regressor. > I would appreciate any ideas about this issue. > > Many thanks, > TH