They describe different software.  The VBM8-Manual describes processing via the VBM8 toolbox, whereas VBMclass10 describes using SPM8 itself.  The VBM8 toolbox will give more sensitive results than using New Segment in SPM8 (although maybe not if SPM12 was used instead).

Best regards,
-John



On 22 November 2013 13:58, Rujing Zha <[log in to unmask]> wrote:
Dear all,
I have got two kinds of vbm methods for VBM analysis, which can be download in http://dbm.neuro.uni-jena.de/vbm8/VBM8-Manual.pdf and http://www.fil.ion.ucl.ac.uk/~john/misc/VBMclass10.pdf.
What is difference between the two mauals above? Which one I can use to analyse the gray matter volumn and density between two groups?
All the best.
2013-11-22

Rujing Zha