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Dear Spm users, I am currently working on a project involving Physio-physiological interaction (PPI) analysis and am trying to regress out the WM/CSF time series. So far I have been able to segment the GM/WM/CSF of each subject. I created a binary mask image using image calculator and am trying to extract the time-series using the VOI function. I am running into trouble as the mask image appears to include voxels that are not captured in the functional scan. I get an error: Failed 'Volume of Interest' Error using svd Input to SVD must not contain NaN or Inf. In file "/Applications/spm8/spm_regions.m" (v4513), function "spm_regions" at line 202. In file "/Applications/spm8/config/spm_run_voi.m" (v4269), function "spm_run_voi" at line 69. If VOI is not the right function, what do I use to extract the time series of the WM/CSF to be able to regress them out in a GLM? Any help would be greatly appreciated as I have been stuck on this for a while! Thankyou in advance, Jenna