Hi - I’m guess that the reviewer intended you to correlate the axial/radial diffusivity against the same set of subject regressors as originally done with FA - not against each other? So you can use tbss_non_FA (see wiki) for that? Cheers. On 21 Nov 2013, at 05:10, Jeremy Strain <[log in to unmask]> wrote: > Hello, > A reviewer disagreed with one of our conclusions and suggested we could prove our claim by creating Axial Diffusivity - Radial Diffusivity voxel based correlational maps. I wanted to verify that this can be accomplished by using the AD data as an input and loading the RD data as an additional voxel-dependent EV and setting up the contrast as normal. > > Hypothetically no other variables: > Design: > EV1 > 1 > 1 > 1 > 1 EV2 = RD data > ... > > Contrasts: > > 0 1 --> AD and RD positively correlate > 0 -1 --> AD and RD negatively correlate > > Thanks, > Jeremy --------------------------------------------------------------------------- Stephen M. Smith, Professor of Biomedical Engineering Associate Director, Oxford University FMRIB Centre FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK +44 (0) 1865 222726 (fax 222717) [log in to unmask] http://www.fmrib.ox.ac.uk/~steve --------------------------------------------------------------------------- Stop the cultural destruction of Tibet