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Dear Mailbase I know this query has come up several times in the past but no responses are ever posted - I am not sure if there have been no responses to this question, or if people respond privately?! I am trying to find out if anyone still analyses CBG, or if anyone has an assay for free cortisol (serum). We had an interesting and complex adrenocortical carcinoma patient recently with high serum cortisols but not overtly cushingoid (her presentation was with mass effects and hyperandrogenism), and an undetectable urine free cortisol, suggesting it may have been a raised CBG eg due to oestrogen secretion? Many thanks for your help Fiona Principal Clinical Scientist Barts Health NHS Trust ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/