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Hello, FSL experts According to what I've read in previous posts, you don't usually recommend performing slice-timing correction as it decreases data quality, suggesting instead that temporal derivatives be added in FEAT. I'm performing an ICA-dual regression analysis of resting-state images, but my preprocessing pipeline is done outside of FSL - and we're not performing slice-timing correction for our interleaved acquisition (TR 2s) or adding temporal derivatives. My question is: do you think that not taking into consideration the slice-timing effects can substantially interfere with the final results of a resting-state analysis in a case like this? A paper by Wu et al. (Brain Connectivity, 2011) suggests the effects would be negligible, but I would be very interested in knowing your opinions. Best regards, Carlos