Print

Print


Dear Drew,

For each subject you could first collapse DCMs from multiple sessions to a single session using BPA.

You can then run the procedure described below.

All the best,

Will.

> -----Original Message-----
> From: SPM (Statistical Parametric Mapping) [mailto:[log in to unmask]]
> On Behalf Of Sevel,Landrew S
> Sent: 19 September 2013 17:37
> To: [log in to unmask]
> Subject: Re: [SPM] BPA, BMA v/s FFX, RFX
> 
> Professor Penny and others,
> 
> For a procedure like the one mentioned below, are there any guidelines
> for incorporating subjects with multiple sessions?
> 
> For example, BMS results favored one model across this group, how then
> would I average to acquire parameter strengths and probabilities across
> this group with multiple sessions?
> 
> Best,
> 
> Drew
> 
> On 9/18/13 5:05 AM, "Penny, William" <[log in to unmask]> wrote:
> 
> >Dear Kushal Kapse,
> >
> >Here I would advise using Bayesian Model Averaging to first average
> >over model space.
> >
> >This will produce a single vector of model parameters for each
> subject:
> >
> >w=BMS.DCM.rfx.bma.mEp
> >
> >You can then do t-tests, F-tests or multivariate tests to look for
> >consistency of effects over a group of patients or eg. two-sample
> >t-tests to look for differences between patients and controls.
> >
> >Best wishes,
> >
> >Will.
> >
> >> -----Original Message-----
> >> From: SPM (Statistical Parametric Mapping)
> >> [mailto:[log in to unmask]] On Behalf Of Kushal Kapse
> >> Sent: 05 September 2013 17:16
> >> To: [log in to unmask]
> >> Subject: [SPM] BPA, BMA v/s FFX, RFX
> >>
> >> Hi Peter and SPM users,
> >>
> >> Two months ago we had email conversation about my doubts on DCM. I
> >> finished the analysis and now working on interpretation. I went
> >> through the DCM tutorial and BMA paper to get understanding on what
> >> way to interpret my datasets. I read the book section
> >> http://www.fil.ion.ucl.ac.uk/~wpenny/publications/spm-
> >> book/selection.pdf to understand BMA and BPA. But i have following
> >> question:
> >>
> >> 1- We are specifically looking to understand connectivity in brain
> >> across treatment. This makes us incline to use parameter estimates
> >> over model estimates (BPA over BMA). BUt seems we can only do BPA if
> >> we select FFX and BMA if we select RFX. Why is this? Can I do RFX
> and
> >> then perform BPA? The reason to use RFX is that we are expecting
> >> different cognitive network for each patient. But we want to do
> >> Bayesian Parameter Averaging to interpret how patients connectivity
> >> changes as a measure of treatment across two scans.
> >>
> >> SO my question is , can i do BPA using RFX.
> >>
> >> Your advice will be really helpful again.
> >>
> >> THanks
> >>
> >>
> >