Dear All,

A postdoc position at the University of Geneva to work on lipid kinases is available starting from the 1st of January 2014.

We are seeking a highly motivated and independent postdoc to untangle the regulation of PI3Ks lipid kinases using a multidisciplinary approach based on structural biology.

Competences in cloning, protein expression, purification, crystallization and X-ray crystallography are essential for this post. Additional expertise in biophysical methods such as fluorescence, SPR, ITC, thermophoresis and in cell-based assays would be desirable.

Applicants would integrate a dynamic team within the pharmaceutical biochemistry lab at the school of pharmaceutical sciences, under the supervision of Dr. Oscar Vadas. The project will use structural information obtained from x-ray structures and Hydrogen/deuterium exchange-mass spectrometry (HDX-MS) data to guide biophysical, in vitro activity assays and cellular experiments. The University of Geneva possesses extensive crystallographic resources, including nanoliter-scale liquid-handling robots, in-house X-ray generator and has access to synchrotron beam time. Successful candidate would benefit from the cutting-edge instrumentation in biochemistry, drug discovery and cell biology that is available within the faculty of sciences.

Candidates should send a cover letter, CV and contact information of three references to Oscar Vadas at [log in to unmask]

Best,
Oscar

Oscar VADAS
Maître Assistant
University of Geneva
Pharmaceutical biochemistry
Science II, lab 4-424
Quai Ernest-Ansermet 30
1211 Geneva 4
Tel: +41 22 379 33 76
Mail: [log in to unmask]