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To add to what Andreas said (definitely go for BBR), use skull stripped images. Also, for the SWI, you will probably get better results using the magnitude image rather than the combined phase/magnitude SWI. On Mon, Aug 12, 2013 at 5:05 PM, Matt B <[log in to unmask]> wrote: > Hi there, > > I wondered if I could ask for some tips re co-registering diffusion data to structural data (both WB). I've currently been trying to use FLIRT with the affine 12 param model but doesn't seem to work. Would it be better if I co-register the FA image to the T1? Also interested in registering diff data to SWI. Would FNIRT be a better option? > > Also is it of advantage to skull strip prior to the coregistration? > > Many thanks > > Matt -- Niels Bergsland Integration Director Buffalo Neuroimaging Analysis Center 100 High St. Buffalo NY 14203 [log in to unmask] (716) 859-7677