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Thanks, Anderson for your prompt response. I have BSITD scores for per subject (41 pre-terms (less than 32 weeks) and 16 full-term infants (38 weeks), the pre-term have been age corrected and these scores were taken at term. I have each individual score for corresponding infant. First, I am planning to just correlate the pre-term infants scores with their FA and then MD images. Then in the next analysis, I'd like to do the group comparison between pre-term and term infants' DTI measures and their corresponding scores. Is it possible to do these analysis in randomize? I'd appreciate your help. Thanks, Supreet. On Fri, Aug 9, 2013 at 9:19 AM, Anderson M. Winkler <[log in to unmask]>wrote: > Hi Supreet, > > > On 9 August 2013 13:42, Supreet kaur <[log in to unmask]> wrote: > >> >> Dear FSL experts, >> >> I would like to perform the voxelwise cross subject statistics to >> assess the relationship between FA, AD, and RD and performance scores of >> the infants (pre-terms and term infants) BSITD-III for our DTI cohort. I >> have two concerns: >> > > I guess you scanned both groups (pre-term and term) after they were born, > is this correct? Or did you scan them before birth and you'd like to > compare with BSITD obtained after? > > > 1) For applying the tbss on the non-FA images (I want to input the MD >> images), how do I input all the subject MD images? after I am done with >> the tbss analysis on the FA data. Is >> inside the tbss, does the tbss_non_FA command will automatically read it >> as non-FA images? >> > > Have you checked this page: > http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/TBSS/UserGuide#Using_non-FA_Images_in_TBSS > > > 2) For the randomize, since I'll be correlating the pre-term infant's FA >> and MD images to their mean BSITD-III scores,how can I incorporate the >> BSITD-III scores inside the model? is it going to be the paired t test or >> unpaired one? >> > > You need to give more information. How many BSITD scores do you have per > subject to take the mean? Do you have a matching image for each of these > scores for each subject, or just one image per infant? At which ages were > they (scores and/or images) taken? Are you going to check the relationship > with the MRI measures only for the pre-term or for both groups? > > Depending on what you have and what you'd like to do, the design is going > to be different. > > All the best, > > Anderson > > > >> >> I'd highly appreciate your feedback on this. >> >> >> >> Sincerely, >> >> Supreet >> > > -- Sincerely, Supreet kaur, Biomedical research engineer, Nationwide Childrens Hospital, Columbus, OH (614)355-3509