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Hi Thanks for that. The latest build of OSX pointless gave us the same error (dyld: Symbol not found: __ZNSt11range_errorD1Ev) however the latest Aimless build was able to run successfully. Cheers Sheena On 12/08/2013, at 7:42 PM, Harry Powell <[log in to unmask]> wrote: > Hi > > I noticed last week that, although the CCP4 updater for OSX requires 64-bit (see CCP4 discussions passim), all the executables are 32-bit (or at least in my current copy, updated a few weeks ago). So there is an inconsistency - no doubt this will be sorted out shortly. > > If you want a 64-bit build of Pointless for OSX then see Phil Evans' ftp site - > > ftp://ftp.mrc-lmb.cam.ac.uk/pub/pre > > Use the most recent version - it may solve your problem. > > On 12 Aug 2013, at 03:28, Bosch, Juergen wrote: > >> Hi Sheena, >> >> simple quickfix to your problem: >> a) Run CAD and limit the output resolution on that mtz file so you don't run into the memory allocation error of pointless. >> b) try phenix.xtriage also if it is not a CCP4 program >> >> Jürgen >> >> ...................... >> Jürgen Bosch >> Johns Hopkins University >> Bloomberg School of Public Health >> Department of Biochemistry & Molecular Biology >> Johns Hopkins Malaria Research Institute >> 615 North Wolfe Street, W8708 >> Baltimore, MD 21205 >> Office: +1-410-614-4742 >> Lab: +1-410-614-4894 >> Fax: +1-410-955-2926 >> http://lupo.jhsph.edu >> >> >> >> >> On Aug 11, 2013, at 9:54 PM, Sheena McGowan (Med) wrote: >> >>> Dear all >>> >>> We have been trying to run pointless on a large mtz file which seems to be allocating more than 1.5Gb of memory resulting in the following error: >>> >>> The program run with command: /Applications/ccp4-6.3.0/bin/pointless >>> has failed with error message >>> pointless(507) malloc: *** mmap(size=1577435136) failed (error code=12) >>> *** error: can't allocate region >>> *** set a breakpoint in malloc_error_break to debug >>> >>> We are using OSX 10.8.4 and believe that we need a 64bit version of pointless. >>> >>> Looking at the pre release ftp site, we found the latest versions of pointless compiled for OSX 10.8, however they do not run. >>> >>> dyld: Symbol not found: __ZNSt11range_errorD1Ev >>> Referenced from: /Applications/ccp4-6.3.0/bin/pointless-1.8.7.osx10.8 >>> Expected in: /usr/lib/libstdc++.6.dylib >>> in /Applications/ccp4-6.3.0/bin/pointless-1.8.7.osx10.8 >>> >>> Any help would be greatly appreciated (and any know if there is a upcoming release of a pre-compiled CCP4 OSX-64bit??) >>> >>> Regards >>> Sheena >>> >>> >>> >>> SHEENA McGOWAN | ARC Future Fellow >>> Department of Biochemistry and Molecular Biology >>> MONASH UNIVERSITY >>> Rm 243, Building 77, Wellington Rd, Clayton >>> Victoria, AUSTRALIA 3800 >>> T + 61 3 9902 9309 | F + 61 3 9902 9500 >>> E [log in to unmask] | Skype s.mcgowan >>> W http://www.med.monash.edu.au/biochem/staff/mcgowan.html >>> >>> Australian Society for Biochemistry and Molecular Biology (State Representative) http://www.asbmb.org.au/ >>> >>> 39th Lorne Conference for Protein Structure and Function http://www.lorneproteins.org >>> February 9-13, 2014. Mantra Lorne, Lorne, AUSTRALIA >>> >> >> > > Harry > -- > ** note change of address ** > Dr Harry Powell, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH > Chairman of European Crystallographic Association SIG9 (Crystallographic Computing) > > > > > > > > > SHEENA McGOWAN | ARC Future Fellow Department of Biochemistry and Molecular Biology MONASH UNIVERSITY Rm 243, Building 77, Wellington Rd, Clayton Victoria, AUSTRALIA 3800 T + 61 3 9902 9309 | F + 61 3 9902 9500 E [log in to unmask] | Skype s.mcgowan W http://www.med.monash.edu.au/biochem/staff/mcgowan.html Australian Society for Biochemistry and Molecular Biology (State Representative) http://www.asbmb.org.au/ 39th Lorne Conference for Protein Structure and Function http://www.lorneproteins.org February 9-13, 2014. Mantra Lorne, Lorne, AUSTRALIA