Dear all,
the integrated facility at EMBL Hamburg at the PETRA3
synchrotron in Germany consists of two macromolecular crystallography
beamlines, a BioSAXS beamline and a laboratory for sample preparation and
characterization. For those of you who are interested in a comprehensive
characterization of their sample, it might be worth to consider to extend your
synchrotron visit and include additional experiments.
The integrated facility includes:
- Offline
protein purification and characterization by circular dichroism, dynamic and static
light scattering (can be booked with beamtime)
- Online
gel filtration and light scattering at the BioSAXS beamline
- A
high-throughput crystallization facility
Samples can be shipped, and experiments can
be monitored remotely through a dedicated web interface
- Crystal
screening on the crystallography beamlines
- Quality
control protocols
All incoming samples for crystallization
are tested by mass spectrometry and thermal shift assay, and a report is
returned to the user
- Sample
optimization
- Inhouse thermofluor screens to optimize
purification, conditioning and crystallizability
- Limited proteolysis
- Expert
staff that assists in the planning, execution and analysis of experiments
Access
to these facilities is funded by the European Union under the FP7 Biostruct-X
grant. For more information on gaining sponsored access please visit:
For
more information on the facilities, please visit:
Best
regards,
Rob
Meijers
Group Leader
EMBL Hamburg Outstation
P: +49 40 89902 243 EMBL c/o DESY
F: +49 40 89902 149 Notkestrasse 85
D-22603 Hamburg, Germany
