But often those using the abbreviation do not know what they mean. How about an "ELIZA test" Something to do with Eliza Doolittle?
John
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Reynolds Tim (RJF) BHFT
Sent: 28 August 2013 15:24
To: [log in to unmask]
Subject: Re: What is an RIA?
It depends who you are:
"When I use a word," Humpty Dumpty said, in rather a scornful tone, "it means just what I choose it to mean-neither more nor less."
in Alice through the Looking glass
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Prof. Tim Reynolds
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From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Prof TS Pillay
Sent: 28 August 2013 3:17 PM
To: [log in to unmask]<mailto:[log in to unmask]>
Subject: What is an RIA?
Dear members of the mailing list,
I have a simple (perhaps trivial even) but important question.
I have come across several relatively recent review articles in good journals where reference is made to the Diasorin Liaison nonisotopic/nonradioactive Vit D assay as a "radioimmunoassay" because it is based on the format of a previous RIA, i.e. uses an antibody as the capture reagent and a radiolabelled analyte analogue
to compete. The new assay uses Chemiluminescence and Diasorin calls it a CLIA, which is fine.
However, the articles insist on calling the CLIA assay an "RIA" even and another assertion is made (not by the same source) that since chemiluminescence
is a form of radiation, the RIA term still applies.
I would be grateful for collective thoughts on this.
Thanking you in advance
Tahir Pillay
--
Prof T.S. Pillay, MBChB, PhD, FRCPath, FCPath
Professor & Head
Department of Chemical Pathology
Faculty of Health Sciences
University of Pretoria
Pretoria
South Africa
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