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Dear Aser, The devil's in the detail. Try the methods for constructing a symmetrical template (and performing an asymmetry analysis) in the following paper by Didelot et al.: http://www.ncbi.nlm.nih.gov/pubmed/21051649 Good luck, All the best, Alexander ----------------------------- Alexander Hammers, MD PhD Chair in Functional Neuroimaging Neurodis Foundation http://www.fondation-neurodis.org/ Postal Address: CERMEP – Imagerie du Vivant Hôpital Neurologique Pierre Wertheimer 59 Boulevard Pinel, 69003 Lyon, France Telephone +33-(0)4-72 68 86 34 Fax +33-(0)4-72 68 86 10 Email [log in to unmask];[log in to unmask] --------------------------------- Other affiliations: Visiting Reader Faculty of Medicine Imperial College London, UK --------------------------------- Honorary Reader in Neurology Department of Clinical and Experimental Epilepsy National Hospital for Neurology and Neurosurgery/ Institute of Neurology, University College London, UK On 23 juil. 2013, at 16:43, fMRI wrote: > Hi all, > > If I want to compare right versus left in the brain, should I use a symmetric template if yes how I can do this or where I find it? > > I could manage to reorient different right contrast images or left to be in the opposite side. But I am not sure how to do this in the template. Can you guide me please > > Regards, > > ASer