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Inclusive masking -- simple mask the results, but the significance is based on the whole brain data. SVC -- mask the results, recompute the significance based on the reduced search volume. You could use the inclusive mask if you wanted to show only a portion of the results and correct for the number of comparisons at the whole brain level. Best Regards, Donald McLaren ================= D.G. McLaren, Ph.D. Research Fellow, Department of Neurology, Massachusetts General Hospital and Harvard Medical School Postdoctoral Research Fellow, GRECC, Bedford VA Website: http://www.martinos.org/~mclaren Office: (773) 406-2464 ===================== This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is intended only for the use of the individual or entity named above. If the reader of the e-mail is not the intended recipient or the employee or agent responsible for delivering it to the intended recipient, you are hereby notified that you are in possession of confidential and privileged information. Any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited and may be unlawful. If you have received this e-mail unintentionally, please immediately notify the sender via telephone at (773) 406-2464 or email. On Tue, Jul 2, 2013 at 11:56 AM, Jon Brock <[log in to unmask]>wrote: > Hi, > > Previously I had assumed that inclusive masking and small volume > correction amount to the same thing. However that does not appear to be the > case (at least for me anyway!). I have been trying to unpack an interaction > with simple paired-t tests. If i inclusively mask with an image generated > from the significant interaction no voxels survive correction, but if I > chose small volume correction, then select the same interaction image I do > get significant results. Could anyone explain the difference between > inclusive masking and small volume correction (and, assuming they are > different and I am not in error) why/when you would select an inclusive > mask? > > Cheers >