one other question. If i take uneven data like


1) Alzheimer's Disease                3 patients
2) Normal Ageing                (Control Group)   1 patient
3) Idiopathic Parkinson             1 patient
4) MCI                                    3 patients


What kind of registration s best suited for this age group and data type? would modelling work on this type of data more nicely then single patient analysis?

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Date: Sun, 14 Jul 2013 15:28:03 +0100
From: [log in to unmask]
Subject: Re: [FSL] Randomise- on mutiple group of subjects
To: [log in to unmask]

No - you need one EV per group. But if you really only have one subject per group, no modelling is going to work. 

Steve. 

--------------------

Stephen M. Smith,  Professor of Biomedical Engineering

Associate Director,   Oxford University FMRIB Centre

FMRIB, JR Hospital, Headington,

Oxford. OX3 9 DU, UK

+44 (0) 1865 222726  (fax 222717)

[log in to unmask]

http://www.fmrib.ox.ac.uk/~steve

----------------------

On 14 Jul 2013, at 15:23, Nida Sajjad <[log in to unmask]> wrote:

Hi,
Thanks for your help and I have created the .mat and .con files.

I have DTI data of 4 groups comprising of 1 patient each. The alphabetical order of the patients in all-skeletonized-FA is following:

1) Alzheimer's Disease
2) Normal Ageing                (Control Group)
3) Idiopathic Parkinson
4) MCI

In order to do the comparison of each group with the control group of normal ageing, I created the following design.mat and design.con files. Can you kindly review and let me know if I am correct?

--------------------------------(design.mat)---------------------------------------

/NumWaves 2
/NumPoints 4
/PPheights 1 1
/Matrix
0 0
0 1
1 0
1 1

--------------------------------(design.con)---------------------------------------

/NumWaves 2
/NumContrasts 2
/PPheights 1 1
/Matrix
1 -1
-1 1


Thank you in anticipation,

Best,