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Dear FSL experts, I am having a big problem I do not understand. I wanted to draw a ROI in the medial frontal cortex (22-42-13). These are the coordinates for that location that have been taken from a template in MNI space at a 4mm of resolution. I followed these steps: 1. echo "22 42 13" | std2imgcoord -img MNI_4mm -std MNI_4mm -vox - *17 42 21.25 *2. fslmaths MNI_4mm -mul 0 -add 1 -roi *17* 1 *42* 1 *21.25* 1 0 1 -kernel sphere 10 -dilF medial_frontal_cortex_roi 3. fslmaths medial_frontal_cortex_roi -thr 0.5 -bin medial_frontal_cortex_roi_mask And the roi is created in the frontal pole instead than in the medial frontal cortex... Any of you could explain me where could be the problem? Thanks a lot for your patience, Yours sincerely, Rosalia.