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The amylase creatinine clearance ratio used to be in vogue  to differentiate hyperamylasaemia due to acute pancreatitis from other causes, the ACCR is > 5% in acute pancreatitis and less than 5% in other conditions associated with hyperamylasaemia. Also in late presenting acute pancreatitis patients, urinary amylase tend to stay elevated for >72 hours.

Regards

Mohammad

Dr. M A Al-Jubouri, MB ChB, MSc, EurClinChem, FRCP Edin, FRCPath
Consultant Chemical Pathologist


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On Wed, 26/6/13, Colley, Michael <[log in to unmask]> wrote:

 Subject: Re: Urinary amylase
 To: [log in to unmask]
 Date: Wednesday, 26 June, 2013, 14:45
 
 Your mailing stimulated me to survey
 our usage.
 
 
                
 Samples NEQAS
 2010             
 13              33
 2011           
    1           
   33
 2012           
    6           
   36
 2013(so far)   4       
           15
                
 ------  -----
                
   24         
    117
 
 Of these there have been 3 high urine amylase values, of
 which 2 had elevated serum amylase. The other had no serum
 amylase associated with it.
 
 On the other hand there were 5 elevated serum amylases with
 normal associated urine amylase.
 
 As you say, is this a worthwhile test?
 
 Michael
 
 -----Original Message-----
 From: Clinical biochemistry discussion list [mailto:[log in to unmask]]
 On Behalf Of Woodrow Iain
 Sent: 26 June 2013 12:10
 To: [log in to unmask]
 Subject: Urinary amylase
 
 Dear Mailbase users,
 
 We currently offer urinary amylase but a recent audit showed
 that we are
 receiving an average of just over one patient test a month,
 plus
 analysing some 5 times this number in EQA samples. However,
 in addition
 to serum amylase, we also have serum lipase as an additional
 test for
 pancreatitis, so are considering removing the urine test
 from our
 routine repertoire.
 
 Have any users done this and, if so, have you encountered
 any problems
 from service users?
 
 
 Regards,
 Iain
 
 Dr Iain Woodrow,
 Clinical Biochemist
 Department of Clinical Biochemistry
 Pinderfields General Hospital
 Aberford Rd
 Wakefield
 WF1 4DG
 
 Phone 01924 317061 or 317000
 
 We're now on Twitter!
 Follow us:
 @MidYorksPathLab
 
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------ACB discussion List Information--------
This is an open discussion list for the academic and clinical community working in clinical biochemistry.
Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
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http://www.laboratorymedicine.nhs.uk
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