She is not on any medications.
Thanks
Fayha
-----Original Message-----
From: Mohammad Al-Jubouri [mailto:[log in to unmask]]
Sent: 19 June 2013 16:19
To: [log in to unmask]
Subject: Re: Water deprivation test query
Hi Fayha,
The response to WDT+DDAVP suggests nephrogenic DI. Serum sodium & osmolality is not consistent with psychogenic polydipsia. Is she on Lithium?
Regards
Mohammad
Dr. M A Al-Jubouri, MB ChB, MSc, EurClinChem, FRCP Edin, FRCPath Consultant Chemical Pathologist
--- On Wed, 19/6/13, Ahmed, Fayha Salah wrote:
> From: Ahmed, Fayha Salah
> Subject: Water deprivation test query > To: [log in to unmask] > Date: Wednesday, 19 June, 2013, 15:50 > > > > > > > > Dear > Colleagues, > > A 26yr old > female presenting with a 6 year history of polydipsia and > polyuria following a > severe road traffic accident.
>
> Normal renal
> function; eGFR >60
>
> Euthyroid.
>
> Calcium, potassium
> and glucose within reference range. Urine dipstick > NAD.
>
>
>
> Water deprivation
> test
> results:
>
>
>
>
>
>
>
>
>
>
> Weight (kg)
>
> Urine Vol mls
>
> S. Na mmol/L
>
> S. Osmo mmol/L
>
> Urine Osmo mmol/L
>
> Urine Na mmol/L
>
> Urine urea
> mmol/L
>
>
> Sample 1
>
> 65.2
>
> 104
>
> 143
>
> 297
>
> 616
>
> 138
>
> 207.1
>
>
> Sample 2
>
> 64.8
>
> 50
>
> 145
>
> 299
>
> 600
>
> 149
>
> 217.4
>
>
> DDAVP
> 2ug IM
>
>
> 30 min post
>
>
>
> 27
>
> 142
>
> 291
>
> 601
>
> 133.2
>
> 207.0
>
>
> 2h post
>
>
>
> 37
>
> 144
>
> 297
>
> 645
>
>
>
>
>
>
>
>
> Could this be
> explained by chronic polydipsia? Any suggestions > > > Thank > you > Fayha > > > > > Dr Fayha > Ahmed > SpR Chemical Pathology > ------ACB discussion List Information-------- > This is an open discussion list for the academic and > clinical community working in clinical biochemistry.
> Please note, archived messages are public and can be viewed > via the internet. Views expressed are those of the > individual and they are responsible for all message content.
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