PLEASE NOTE: previous candidates need not apply.
An exciting opportunity has arisen for an ambitious and talented statistician, with an interest in genetics, to join an interdisciplinary team working on large-scale genetic studies of cardiovascular disease at the Cardiovascular Epidemiology Unit at the University of Cambridge. The Cardiovascular Epidemiology Unit (CEU) conducts world-leading interdisciplinary research into the prediction and prevention of cardiovascular disease, with a portfolio of studies that comprises >2.5 million participants and is currently, expanding into genetics. Professor John Danesh is the Unit's overall Director, Professor Simon Thompson is the Unit's Director of Research in Biostatistics and Dr Jo Howson leads statistical genetics.
The post holder will be expected to design and implement analyses of genetic datasets from large consortia in relation to cardiovascular disease and its risk factors. Specific examples of these analyses include (but are not limited to):
- analyses of common, low-frequency and rare variants in population-based studies of discrete and quantitative traits;
- fine-mapping and multi-marker tests to locate causal variants;
- pathway analysis using rare and common variants;
- integration of genetic data with biochemical factors for the assessment of causality ("Mendelian Randomisation");
The post holder will also be expected to advise on appropriate statistical practices, and test and develop the statistical methods necessary to evaluate hypotheses of interest, such as those listed above. The work of the post holder is expected to lead to high-impact publications.
The post-holder will have: (1) relevant qualifications e.g,, a postgraduate degree in statistics, biostatistics, genetic epidemiology or similar, (2) a sound understanding of statistical concepts, ideally in relation to chronic disease epidemiology (3) strong quantitative skills, including experience of using relevant statistical software (STATA, R), (4) high level report writing and presentational skills, (5) a working knowledge of genetics is desirable but not essential. The post-holder should also be able to work independently, accurately judge priorities, and have excellent organisational and communication skills.
This position can be filled by an appropriate candidate at Senior Research Associate, Research Associate or Research Assistant level, depending on relevant qualifications and experience. Senior Research Associate is awarded on the basis of individual merit and may be awarded to the successful candidate if approved by the Faculty Board of the Cambridge School of Clinical Medicine.
Details of how to apply are available at http://www.phpc.cam.ac.uk/jobs
Informal enquiries can be made to Dr Jo Howson by email ([log in to unmask]) or telephone + 44 (0) 1223 740078.
Location of post: Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge, CB1 8RN
ALL APPLICATIONS MUST BE RECEIVED BY 5PM ON THE CLOSING DATE
*The funds for these posts are available until 31 December 2015 in the first instance.
Please quote reference RH01195 on all correspondence about this post.
Closing date: Friday 7 June.
Interview Date(s): w/c 24 June 2013
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