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However, a reviewer could reject the method on theoretical grounds - the explanation of X-ray diffraction as a multi-photon process is not correct.... BR -----Original Message----- From: CCP4 bulletin board [mailto:[log in to unmask]] On Behalf Of Peter Artymiuk Sent: Friday, April 19, 2013 7:11 AM To: [log in to unmask] Subject: Re: [ccp4bb] popular piece on X-ray crystallography Just to clarify, Jeremy was not being serious, but imagining what an awkward / obnoxious grant reviewer might have said in 1913. But your points would be valuable in rebutting such a view Pete On 19 Apr 2013, at 11:28, Navdeep Sidhu wrote: > Dear Pet, > > On the contrary, far as I know, nature seems to require most solids we > see around us to be crystalline. And much of the rest is either > gaseous or plasma. Hence, by the reasoning proposed, we are led to > suspect a different conclusion: that it's studies dealing with the > remaining state that have "little general applicability as the > requirement for objects to force themselves into" the disordered > arrays of the liquid state "is an absurd limitation." (However, I'd > support funding it nevertheless.) > > Best regards, > Navdeep > > > --- > On Fri, Apr 19, 2013 at 10:14:04AM +0100, Peter Artymiuk wrote: >> Another of my colleagues, Jeremy Craven, is an NMR spectroscopist and bioinformatician. He is in referee mode at present and comments: >> >> >>> From: Jeremy Craven <[log in to unmask]> >>> Date: 19 April 2013 10:05:18 GMT+01:00 >>> To: Peter Artymiuk <[log in to unmask]> >>> Subject: Re: Fwd: popular piece on X-ray crystallography >>> >>> I suspect this technique will have little general applicability as the requirement for objects to force themselves into ordered arrays is an absurd limitation. I would not support funding it. >>> >>> Jeremy >> >> >> I fear he may be right >> >> best wishes >> Pet >> >> >> >> >> On 19 Apr 2013, at 09:53, David Briggs wrote: >> >>> Following on from that - readers may be interested in Stephen >>> Curry's post in the Guardian, regarding the Crystallography exhibit >>> at the London Science Museum. >>> >>> http://www.guardian.co.uk/science/occams-corner/2013/apr/19/1 >>> >>> regards, >>> >>> Dave >>> >>> ============================ >>> David C. Briggs PhD >>> http://about.me/david_briggs >>> >>> >>> On 19 April 2013 09:44, Peter Artymiuk <[log in to unmask]> wrote: >>>>> >>>> >>>> Dear all >>>> >>>> In Britain there is a free newspaper that you can pick up on buses called the Metro. My colleague Geoff Ford pointed out this short feature on the history X-ray crystallography in last Monday's Metro newspaper. I think it's rather good. >>>> >>>> http://www.cosmonline.co.uk/blog/2013/04/14/conquering-realm-invisi >>>> ble >>>> >>>> best wishes >>>> Pete >>>> >>>> >>>> >>>> Prof Peter Artymiuk >>>> Krebs Institute >>>> Department of Molecular Biology & Biotechnology University of >>>> Sheffield Sheffield >>>> S10 2TN >>>> ENGLAND > > > --- > Navdeep Sidhu > Departments of Structural Chemistry > & Pediatrics II > University of Goettingen > Office Address: > Institute of Inorganic Chemistry > Tammannstrasse 4 > 37077 Goettingen > Germany > Email: [log in to unmask] > Phone: +49 551 39 33059 > Fax: +49 551 39 22582 > Dept. Homepage: http://shelx.uni-ac.gwdg.de/ > --- Prof Peter Artymiuk Krebs Institute Department of Molecular Biology & Biotechnology University of Sheffield Sheffield S10 2TN ENGLAND