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Check the initial alignment between the images (Check Reg).  I'd expect the plots to look like this if there is zero overlap between the images.

Bets regards,
-John

On 24 March 2013 18:50, shiliang huang <[log in to unmask]> wrote:
Dear Experter
 
I want to use SPM to do coregister. I imported the reference image and the source image and the image series. It gave the following figure during it was runing. It seems like giving out different  figure compared before. What is the reason?