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Dear Donald McLaren: I'm so thankful to all of you! Sincerely, Bin-Ke 2013/3/5 MCLAREN, Donald <[log in to unmask]> > You need to apply the coregistration parameters to the CBF image before > normalization. > > Best Regards, Donald McLaren > ================= > D.G. McLaren, Ph.D. > Research Fellow, Department of Neurology, Massachusetts General Hospital > and > Harvard Medical School > Postdoctoral Research Fellow, GRECC, Bedford VA > Website: http://www.martinos.org/~mclaren > Office: (773) 406-2464 > ===================== > This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED > HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is > intended only for the use of the individual or entity named above. If the > reader of the e-mail is not the intended recipient or the employee or agent > responsible for delivering it to the intended recipient, you are hereby > notified that you are in possession of confidential and privileged > information. Any unauthorized use, disclosure, copying or the taking of any > action in reliance on the contents of this information is strictly > prohibited and may be unlawful. If you have received this e-mail > unintentionally, please immediately notify the sender via telephone at > (773) > 406-2464 or email. > > > On Mon, Mar 4, 2013 at 9:30 PM, Bin-Ke YUAN <[log in to unmask]> wrote: > >> Dear Wang, >> Thanks for your reply! If I correctly understand you: Firstly, the >> control image was corregistered with the corresponding T1 >> image;Secondly,the T1 image were normalized to MNI space;Finally,the CBF >> images (1.72x1.72x3) were spatially normalized and re-sampled (2x2x2 mm) >> using the normalization parameters estimated during the previous T1 >> normalization. Is the procedure right or suitable? >> sincerely, >> Bin-Ke >> >> >> 2013/3/5 Ze Wang <[log in to unmask]> >> >>> Hi Bin-Ke, >>> GE ASL sequence produces mean control image (regular FSE image) >>> and mean CBF map (or the mean perfusion difference map if the scale is not >>> within 0-100). To register cbf map to T1, you'd better use the mean control >>> image rather than the cbf map, then apply the same transformation to the >>> cbf map. This process is the same for any vendor. You can find more >>> information in the manual available in >>> cfn.upenn.edu/~zewang/ASLtbx.php >>> >>> Best >>> Ze >>> >>> On 3/4/2013 5:51 AM, Bin-Ke YUAN wrote: >>> >>> Dear all: >>> I used unified segmentation to perform normalization of my CBF images >>> and found the normalization effect was bad (images of unnormalized and >>> normalized were attached). I have done the corregister before normalization. >>> The pulse sequence of ASL are 3DASL (no contrast,GE healthcare MR-750 >>> 3.0 T scanner) and the CBF images were got using the 3DASL functiontool of >>> the scanner. >>> Any suggestion / advice will be very welcome. >>> >>> Many thanks in advance, >>> Bin-Ke >>> >>> >>> >>> -- >>> -------------------------------------------------- >>> Ze Wang, Ph. Dhttp://cfn.upenn.edu/~zewang >>> Research Assistant Professor of Biomedical Engineering, >>> Departments of Psychiatry and Radiology, >>> Perelman School of Medicine, >>> University of Pennsylvania, >>> 3900 Chestnut Street, >>> Philadelphia, PA 19104, USA >>> Tel: 215-222-3200 ext 123 >>> Fax: 215-386-6770 >>> >>> >> >