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Jason, The best way to do this is to contrast the 2 variables in the 1st level model, then use a one-sample t-test with a covariate. As it sounds like you have an imaging covariate, you will also need to use the Biological Parametric Mapping Toolbox from Wake Forest. Best Regards, Donald McLaren ================= D.G. McLaren, Ph.D. Research Fellow, Department of Neurology, Massachusetts General Hospital and Harvard Medical School Postdoctoral Research Fellow, GRECC, Bedford VA Website: http://www.martinos.org/~mclaren Office: (773) 406-2464 ===================== This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is intended only for the use of the individual or entity named above. If the reader of the e-mail is not the intended recipient or the employee or agent responsible for delivering it to the intended recipient, you are hereby notified that you are in possession of confidential and privileged information. Any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited and may be unlawful. If you have received this e-mail unintentionally, please immediately notify the sender via telephone at (773) 406-2464 or email. On Wed, Mar 13, 2013 at 8:41 AM, Jason Love <[log in to unmask]>wrote: > Dear SPMers, > > I'd hope to perform the repeated measure ANOVA in order to see the > difference between two variables while accounting for one covariate at the > 2nd level in SPM8. > > I have generated the beta map for each variable in all subjects, but I'm > not sure how to enter those three beta maps for the group analysis. > > If anyone has experiences on it, please help, > > Jason > > >