hi - am replying to my own question raised a few weeks ago, namely how to relate resting state data to task-data I got from the same Ps From what I have gathered, one nice and simple approach in FSL would be this. Could you please comment if this is sensible? I have a posterior parietal network engaged during my experimental task, so one hypothesis I want to test is that parietal responses at rest may correlate with task-based responses. To do this 1. Use concat ICA in my resting data to derive networks 2. Select the components with posterior parietal involvement 3. Use dual regression to get individual maps 4. Derive masks based on the task data around the peaks of posterior parietal clusters (PPCs). 5. Use fslmeants to derive an integration measure of these PPCs masks in the resting state data within the selected ICs involving parietal cortex this would be something like for each subject fslmeants -i dr_stage2_[IC_InvolvingParietal] -o integrat_score.txt -m PPC_mask_from task data This would give me for each P, the strenght of the correlation between the PPC voxels with the rest of the network 6. Extract the percent signal change from the PPC response in the task data and correlate it with the integration scores as derived by (5) Significant correlation would indicate that the degree of the integration of PPC at rest (e.g, within the right frontoparietal IC) is 'predictive' of the PPC response during my task paradigm. does this make some sense? thanks in advance of any advise cheers, david