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Dear Mailbase,
 
We have experienced noticable bottle-to-bottle variation with Biorad's urine Lyphochek II lot 63312 with normetanephrine/noradrenaline values falling by 50% of previously expected values and also androsterone/aetiocholanolone and THE showing similar drops. 
 
It seems to be a pack issue in that taking a bottle from a different pack (of a dozen) gives expected results. Lypho I is not showing the same intra-pack variation.
 
Has anyone experienced similar problems?
Best wishes
John       
 
 
John Christofides
Principal Clinical Scientist
Chemical Pathology Department
Epsom and St Helier University Hospital NHS Trust
Epsom Hospital
Epsom, Surrey
KT18 7EG
UK
Phone: +44(0)1372 735982
Fax: +44(0)1372 735498
Email: [log in to unmask]
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