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Hi there, I am trying to do ICA analysis on rat brain experiencing silent seizure activity in a model of absence epilepsy. I've run the data through MELODIC and it finds 17-20 components. However, when I look at the spatial maps of the components, I see that many of the ICs basically show complete activation of all brain pixels belonging to a single slice. I have 8 slices in my imaging volume, and 8 IC maps show whole-brain activation in individual slices. I was thinking perhaps it was due to the motion correction, since I assume that the correction is done on a per-slice basis. However, when I turn off MCFLIRT I get the same behaviour. Would you have any thoughts as to what might be causing this apparent artifact? Thanks for your help! -andrew