Dear all FSL experts
Currently, i want to analysis the 3-yr longitudinal DTI dataset with TBSS protocol. After searching the PUBMED and FSL archive, i found there are two major approach for such kind of analysis: A. treated the longitudinal data as cross-section data and perform longitudinal based statistical permutation analysis; B. using half-way space (using FLIRT and midtrans?) registration scheme for the longitudinal DTI data and also perform longitudinal based statistical permutation analysis. Because of some clinical issues, it is hard to let all the subjects have 3 time-point scans, in the current study design, i just include the subject at least have 2 time-point scans into the analysis procedure (of course, most of subjects could have 3 time point scans !). Based on above situation which i faced, which analysis pipeline would be most optimal for this study? Any helps and related opinions were welcome !
Many thanks
Best
Paul