Print

Print


Ok, Mark!

Thanks a lot for your help!

Patricia.

2013/1/21 Mark Jenkinson <[log in to unmask]>

>  Hi,
>
>  That looks right - any pairwise difference will be detected with this
> F-test and so it is looking for any departure from the mean, as an ANOVA
> would.  The randomise call looks correct to me, and will generate results
> for both the t-contrasts and the f-contrast.
>
>  All the best,
> Mark
>
>
>  On 21 Jan 2013, at 14:02, Patricia Pires <[log in to unmask]> wrote:
>
> Dear Mark,
>
> following your advice, i have designed the following matrix (attached).
>
> Now should i have to run randomise. Is this command correct correct?:
>
> *randomise -i all_FA_skeletonised.nii -m mean_FA_skeleton_mask.nii -o
> resultados_TBSS -d matriz.mat -t matriz.con -f matriz.fts -n 5000 --T2 -V*
>
> Then, if there is any result, would it be from an ANOVA with post-hoc,
> right?
>
> Thank you very much for your help!
>
> Patricia.
>
> 2013/1/21 Mark Jenkinson <[log in to unmask]>
>
>> Dear Patricia,
>>
>>  Just include 1, 3 and 5 only.
>> There are other combinations that would be equivalent, but you must
>> restrict it to linearly independent contrasts, and 1, 3 and 5 are the
>> simplest set of those.  Any other contrast you added to them could be
>> generated by a linear combination of these three.  And so that is why I
>> chose these.
>>
>>  All the best,
>> Mark
>>
>>
>>
>>
>>  On 21 Jan 2013, at 10:00, Patricia Pires <[log in to unmask]>
>>  wrote:
>>
>> Hello Mark,
>>
>> thank you very much for your answer. I am not very sure what do you mean
>> when you say "*include one F-test that consisted of t-contrasts 1, 3 and
>> 5." *Does it mean that my contrast are allright but i have to include
>> option F-test=1 and mark t contrast 1, 3 and 5? Why only these contrast?
>>
>> On the other way, should my randomise command be different than:
>>
>> randomise -i all_FA_skeletonised.nii -m mean_FA_skeleton_mask.nii -o
>> resultados_TBSS -d matriz.mat* -t matriz.con* -n 5000 --T2 -V
>>
>> -t option in randomise should now be -f because of the F-test analysis?
>>
>> Thank you very much,
>>
>> Patricia.
>>
>>
>> 2013/1/19 Mark Jenkinson <[log in to unmask]>
>>
>>> Hi,
>>>
>>> If you want a single F-test that checks for any differences then it
>>> would be sufficient to use your existing t-contrasts and include one F-test
>>> that consisted of t-contrasts 1, 3 and 5.
>>>
>>> All the best,
>>>         Mark
>>>
>>>
>>>
>>> On 17 Jan 2013, at 11:42, SUBSCRIBE FSL Patricia Pires <[log in to unmask]>
>>> wrote:
>>>
>>> > Dear fsl list,
>>> >
>>> > i have 4 different groups to analize FA index. I performed a Glm
>>> matrix:
>>> >
>>> > /Matrix
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 1.000000e+00  0.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  1.000000e+00    0.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    1.000000e+00    0.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> > 0.000000e+00  0.000000e+00    0.000000e+00    1.000000e+00
>>> >
>>> > And their contrasts:
>>> >
>>> > /Matrix
>>> > 1.000000e+00 0.000000e+00 -1.000000e+00 0.000000e+00
>>> > -1.000000e+00 0.000000e+00 1.000000e+00 0.000000e+00
>>> > 1.000000e+00 0.000000e+00 0.000000e+00 -1.000000e+00
>>> > -1.000000e+00 0.000000e+00 0.000000e+00 1.000000e+00
>>> > 1.000000e+00 -1.000000e+00 0.000000e+00 0.000000e+00
>>> > -1.000000e+00 1.000000e+00 0.000000e+00 0.000000e+00
>>> > 0.000000e+00 0.000000e+00 1.000000e+00 -1.000000e+00
>>> > 0.000000e+00 0.000000e+00 -1.000000e+00 1.000000e+00
>>> > 0.000000e+00 -1.000000e+00 1.000000e+00 0.000000e+00
>>> > 0.000000e+00 1.000000e+00 -1.000000e+00 0.000000e+00
>>> > 0.000000e+00 -1.000000e+00 0.000000e+00 1.000000e+00
>>> > 0.000000e+00 1.000000e+00 0.000000e+00 -1.000000e+00
>>> >
>>> >
>>> > There are two contrast with significant results when i run randomise:
>>> >
>>> > randomise -i all_FA_skeletonised.nii -m mean_FA_skeleton_mask.nii -o
>>> resultados_TBSS -d matriz.mat -t matriz.con -n 5000 --T2 -V
>>> >
>>> > However this procedure has been criticized because there is not a
>>> previous overall of results and i am wondering if i first have to do a
>>> F-tests:
>>> >
>>> > http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/FEAT/UserGuide#F-Tests
>>> >
>>> > I have to do a F-test first? In that case, what will indicate these
>>> results:
>>> >
>>> > - C1: Group A        1  0  0  0
>>> >
>>> > (if i found results here, e.g. cluster
>>> --in=resultados_FA_mean_FA_skeleton_mask_tfce_corrp_tstat1.nii.gz
>>> --thresh=0.95), would this indicating Group A differ from other groups and
>>> then i could finally do my first procedure? Or it is not necessary this
>>> first F-test analysis?
>>> >
>>> > Thanks in advance,
>>> >
>>> > Patricia.
>>>
>>
>>
>>
> <GlmANOVAMark.png>
>
>
>