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Best place to start:

http://scottlab.ucsc.edu/~wgscott/xtal/wiki/index.php/Crystallography_on_OS_X


------------------------------------------
A. Radu Aricescu, PhD
University Research Lecturer

University of Oxford
Wellcome Trust Centre for Human Genetics
Division of Structural Biology
Roosevelt Drive, Oxford OX3 7BN
United Kingdom
Phone: +44-1865-287564
Fax: +44-1865-287547


---- Original message ----
>Date: Mon, 28 Jan 2013 17:09:30 +0800
>From: CCP4 bulletin board <[log in to unmask]> (on behalf of LISA <[log in to unmask]>)
>Subject: [ccp4bb] install crystallography software on mac  
>To: [log in to unmask]
>
>   Hi all,
>   I am trying to install ccp4, phenix, coot and other
>   crystallography software on my mac. I am not
>   familiar with mac, neither Linux system. Please give
>   me some protocols to install these software and how
>   to update them. I appreciate it.
>
>   Lisa