***NB: Posted on behalf of Dr. Macedo-Ribeiro,
whom you should contact for further information (e-mail address below).***
The Associate Laboratory IBMC-INEB is
recruiting a highly motivated researcher to integrate a multidisciplinary
team in the field of the Biochemistry and Structural Biology of enzymes
associated with human diseases. A PhD in the appropriate disciplines is
mandatory. Previous post-doctoral research experience and demonstrated
skills in Biochemistry and Structural Biology are required.
Contract:
The fixed term contract is limited
to 28 months and expected to begin on March 1st 2013. The monthly gross
salary amounts to 3.191,82 Euros.
Job description:
The regulation of biological and pathological
processes is achievable through specific inhibition, spatial and temporal
compartmentalization, and post-translational modification of the intervening
enzymes. Impairment of any of these regulative mechanisms often results
in serious pathologies to which specific therapeutic approaches can be
conceived by understanding the molecular details of enzyme specificity,
as well as of their strict regulation. In order to address the role played
by macromolecular interactions and/or regulation by post-translational
modifications in enzyme activity and specificity, we use protein X-ray
crystallography along with a plethora of complementary biophysical/biochemical
techniques.
We are especially interested in elucidating
the molecular mechanisms of action of proteins associated with neurodegenerative
and infectious diseases (http://www.ibmc.up.pt/research/research-groups/protein-crystallography).
Application deadline: 20/01/2013
All details required for application
can be found at:
http://www.eracareers.pt/opportunities/index.aspx?task=global&jobId=32498
For more information please contact:
Dr. Sandra Macedo-Ribeiro
Protein Crystallography Group
IBMC- Instituto de Biologia Molecular
e Celular
Rua do Campo Alegre, 823
4150-180 Porto, Portugal
(sribeiro_at_ibmc.up.pt)
--
Pedro J. B. Pereira, PhD
IBMC - Biomolecular Structure Group
Rua do Campo Alegre, 823
4150-180 Porto
Portugal
Tel. +351 226 074 900
Fax +351 226 099 157