Thanks David! ________________________________ From: FSL - FMRIB's Software Library [[log in to unmask]] On Behalf Of David V. Smith [[log in to unmask]] Sent: Wednesday, December 19, 2012 6:40 PM To: [log in to unmask] Subject: Re: [FSL] correlational analysis Hi Helen, You should re-run the randomise stage of dual regression and adjust your model to include your covariate of interest: http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/FEAT/UserGuide#Single-Group_Average_with_Additional_Covariate If you do have two groups and an additional behavioral variable, I would suggest adding the covariate as a third EV. Otherwise, it seems like you might identify group differences that aren't distinct from the covariate. Cheers, David On Dec 19, 2012, at 11:10 AM, Helen Sawaya wrote: Dear all, I have a question regarding correlational analysis in FSL between brain activation and a behavioral variable. I ran groupICA (using MELODIC) then dual regression to investigate the group differences in brain activity in the components of interest (it was a resting state fMRI study). I am interested in seeing whether the significant group difference in brain activity in one of the components correlates with my behavioral measure. I cant seem to find, however, an outputted file for each participant with a statistic measuring their activation for that component so I can run a correlation. Any thoughts? Thanks a lot Helen -------------------------------------------- David V. Smith, Ph.D. Postdoctoral Fellow, Delgado Lab Department of Psychology Rutgers University Newark, NJ 07102 --------------------------------------------