Model and contrasts look fine; however, I'd change the high-pass to 240.

The other things that I would look at are:
(1) Using an uncorrected threshold to look at a single subject. You
don't have that many blocks;
(2) Make sure the timing is correct.
(3) Find a ROI/voxel you expect to be active and see if you can see
the response following a block pattern.

In your design, do you expect the neurons to be on for 21 seconds?

Best Regards, Donald McLaren
=================
D.G. McLaren, Ph.D.
Research Fellow, Department of Neurology, Massachusetts General Hospital and
Harvard Medical School
Postdoctoral Research Fellow, GRECC, Bedford VA
Website: http://www.martinos.org/~mclaren
Office: (773) 406-2464
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On Wed, Nov 7, 2012 at 1:16 PM, Michael Bui <[log in to unmask]> wrote:
> Dear McLaren,
>
> Here I attached the pdf file contain the design matrix and contrast, please
> check it for me.
>
> Thank you very much,
> Best regards,
> Michael Bui
>
>
> On Thu, Nov 8, 2012 at 12:51 AM, MCLAREN, Donald <[log in to unmask]>
> wrote:
>>
>> Can you send me the design matrix and contrast.
>>
>> Best Regards, Donald McLaren
>> =================
>> D.G. McLaren, Ph.D.
>> Research Fellow, Department of Neurology, Massachusetts General Hospital
>> and
>> Harvard Medical School
>> Postdoctoral Research Fellow, GRECC, Bedford VA
>> Website: http://www.martinos.org/~mclaren
>> Office: (773) 406-2464
>> =====================
>> This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED
>> HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is
>> intended only for the use of the individual or entity named above. If the
>> reader of the e-mail is not the intended recipient or the employee or
>> agent
>> responsible for delivering it to the intended recipient, you are hereby
>> notified that you are in possession of confidential and privileged
>> information. Any unauthorized use, disclosure, copying or the taking of
>> any
>> action in reliance on the contents of this information is strictly
>> prohibited and may be unlawful. If you have received this e-mail
>> unintentionally, please immediately notify the sender via telephone at
>> (773)
>> 406-2464 or email.
>>
>>
>> On Wed, Nov 7, 2012 at 12:49 PM, Michael Bui <[log in to unmask]> wrote:
>> > Dear McLaren,
>> > Thank you for your suggestion, do you mean the duration is the length of
>> > stimulus (in this case every eight-image acquisition (21.44sec) the
>> > stimulus
>> > is changed). I have tried the duration to 21.44sec but they do not have
>> > response.
>> >
>> > Please help me to solve this problem,
>> > Best regards,
>> > Michael Bui
>> >
>> > On Thu, Nov 8, 2012 at 12:36 AM, MCLAREN, Donald
>> > <[log in to unmask]>
>> > wrote:
>> >>
>> >> You need to specify a duration unless your using FIR, in which case
>> >> you need to specify the length of the window to look for the response.
>> >> The default duration is 0, so it will look for very short blips in
>> >> your timecourse.
>> >>
>> >> Best Regards, Donald McLaren
>> >> =================
>> >> D.G. McLaren, Ph.D.
>> >> Research Fellow, Department of Neurology, Massachusetts General
>> >> Hospital
>> >> and
>> >> Harvard Medical School
>> >> Postdoctoral Research Fellow, GRECC, Bedford VA
>> >> Website: http://www.martinos.org/~mclaren
>> >> Office: (773) 406-2464
>> >> =====================
>> >> This e-mail contains CONFIDENTIAL INFORMATION which may contain
>> >> PROTECTED
>> >> HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is
>> >> intended only for the use of the individual or entity named above. If
>> >> the
>> >> reader of the e-mail is not the intended recipient or the employee or
>> >> agent
>> >> responsible for delivering it to the intended recipient, you are hereby
>> >> notified that you are in possession of confidential and privileged
>> >> information. Any unauthorized use, disclosure, copying or the taking of
>> >> any
>> >> action in reliance on the contents of this information is strictly
>> >> prohibited and may be unlawful. If you have received this e-mail
>> >> unintentionally, please immediately notify the sender via telephone at
>> >> (773)
>> >> 406-2464 or email.
>> >>
>> >>
>> >> On Wed, Nov 7, 2012 at 12:33 PM, Michael Bui <[log in to unmask]> wrote:
>> >> > Dear SPM experts,
>> >> >
>> >> > Please help me to plot the activation map. I have 128 smoothed fMRI,
>> >> > 16
>> >> > slices/volume, TR = 2.68 and stimuli is:
>> >> > Time Onset
>> >> > 10    0
>> >> > 30    0
>> >> > 50    1
>> >> > 70    0
>> >> > 90    0
>> >> > 110    1
>> >> > 130    1
>> >> > 150    0
>> >> > 170    1
>> >> > 190    0
>> >> > 210    0
>> >> > 230    1
>> >> > 250    1
>> >> > 270    0
>> >> > 290    1
>> >> >
>> >> > I used "Specify 1st-level" and choose "Onsets" values as "50 110 170
>> >> > 230
>> >> > 250
>> >> > 290". Then I follow the prompt of SPM8, estimate and inference,
>> >> > accept
>> >> > the
>> >> > default p-value (0.05), FWE but the result has no activation in the
>> >> > brain.
>> >> > Could you please give me any suggestion to produce the activation
>> >> > map?
>> >> >
>> >> > Thank you very much for your help,
>> >> > With best wishes,
>> >> > Michael Bui
>> >
>> >
>
>