Hi Eugenio, what you want is easily achievable using spm and Matlab functionality. The following should work, although the output is only to the Matlab command window. Watch out for linebreaks when copying. % ==== start ==== % get images to analyze P = spm_select([Inf],'image','Select image(s)', [],pwd,'.*'); % loop over images clc for i = 1:size(P,1); % get current image, filename sub = deblank(P(i,:)); [p, nm, e, v] = spm_fileparts(sub); disp(['... processing image ' nm ' from ' p '...']); V = spm_vol(sub); % load, clean data vol = spm_read_vols(V); vol(isnan(vol)) = 0; vol(~isfinite(vol)) = 0; % find, loop over clusters [clus_vol,number] = spm_bwlabel(vol,18); for ii = 1:number % get coordinates, find center temp = vol .* (clus_vol == ii); coords = find(temp > 0); [out{1:3}] = ind2sub(size(vol),coords); ctr_v = mean(cell2mat(out),1); % convert voxel to mm coordinates ctr_mm = (V.mat(1:3,:) * [ ctr_v 1]')'; % round voxel coordinates ctr_v = round(ctr_v); % output to Matlab window disp([' ... center ' num2str(ii) '/' num2str(number) ' is at voxel ' num2str(ctr_v(1,1)) '/' num2str(ctr_v(1,2)) '/' num2str(ctr_v(1,3)) ', mm = ' sprintf('%02.2f', ctr_mm(1,1)) '/' sprintf('%02.2f', ctr_mm(1,2)) '/' sprintf('%02.2f', ctr_mm(1,3)) ]); end; end; % ==== end ==== Hope this helps, Marko Eugenio Abela wrote: > Dear Experts > > I have one binary image in native anatomical space that consists of ~80 clusters (locations of intracranial electrodes from an intensity segmented skull stripped CT image). I'd like to find the coordinates of this clusters but do not know how to code that in Matlab. Any hints are greatly appreciated. > > Regards > > Eugenio Abela, MD > > Research Fellow > Dep. of Neurology > University Hospital > 3010 Bern/Switzerland > -- ____________________________________________________ PD Dr. med. Marko Wilke Facharzt für Kinder- und Jugendmedizin Leiter, Experimentelle Pädiatrische Neurobildgebung Universitäts-Kinderklinik Abt. III (Neuropädiatrie) Marko Wilke, MD, PhD Pediatrician Head, Experimental Pediatric Neuroimaging University Children's Hospital Dept. III (Pediatric Neurology) Hoppe-Seyler-Str. 1 D - 72076 Tübingen, Germany Tel. +49 7071 29-83416 Fax +49 7071 29-5473 [log in to unmask] http://www.medizin.uni-tuebingen.de/kinder/epn/ ____________________________________________________