Dear Omniscient Mass,
I’ve been discussing with our oncologists the problem of determining ovarian function in patients on aromatase inhibitors.
The general conclusion is that standard Oestradiol immunoassays are not good enough to provide accurate determination of pre/menopausal status in patients to go on these drugs.
The recommendation (J.Clin.Oncol 24:2444-2447;2006) is that an extraction method is used.
Is there anyone out there doing this? It must be a national problem.
Michael