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Dear Mohammad, No he is not cushingoid - investigated only because of incidental finding of adrenal mass. Yes he has normal renal function. The doctor insists that dexamethasone was given correctly on each occassion. Best wishes Fiona On 11/29/12, Mohammad Al-Jubouri <[log in to unmask]> wrote: > Hi Fiona, > > I have only questions I am afraid: > > 1. Is he Cushingoid? you seem to suggest he is not. > > 2. Does he have normal renal function? > > 3. Has he taken/been given dexamethasone? > > And of course normal UFC doesn't exclude Cushing's. > > Regards > > > Mohammad > > > > Dr. M A Al-Jubouri, MB ChB, MSc, FRCP Edin, FRCPath > Consultant Chemical Pathologist > > From: Fiona Davidson <[log in to unmask]> > To: [log in to unmask] > Sent: Thursday, November 29, 2012 12:21 PM > Subject: ? Cushings > > Dear all, > > We currently have a patient very similar to the one posted here by Avril > Wayte in August. > > The patient is a 62 year old gentleman with an incidentally found adrenal > mass, negative screen for phaeo and aldosteronism. Two 24 hour UFC have > been well within the normal range at 38nmol and 44nmol but he has failed to > suppress his cortisol post dexamethasone on several occassions (post dex > cortisol 135-176nmol/L). He is asymptomatic, not obese and not depressed. > > Unlike Avril's patient this gentleman is only on Thyroxine and Aspirin so > drug interfernce seems unlikely? > > Any suggestions would be very welcome! > > Fiona Davidson > Pre-Reg Clinical Biochemist > Kingston Hospital NHS Trust > > ------ACB discussion List Information-------- > This is an open discussion list for the academic and clinical community > working in clinical biochemistry. > Please note, archived messages are public and can be viewed via the > internet. Views expressed are those of the individual and they are > responsible for all message content. > ACB Web Site > http://www.acb.org.uk/ > Green Laboratories Work > http://www.laboratorymedicine.nhs.uk/ > List Archives > http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html > List Instructions (How to leave etc.) > http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/