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Hi - if you're running a full FSLVBM Then I don't think there's too much point in also running SIENAX? Cheers -------------------- Stephen M. Smith, Professor of Biomedical Engineering Associate Director, Oxford University FMRIB Centre FMRIB, JR Hospital, Headington, Oxford. OX3 9 DU, UK +44 (0) 1865 222726 (fax 222717) [log in to unmask] http://www.fmrib.ox.ac.uk/~steve ---------------------- On 8 Oct 2012, at 18:38, Jeremy Strain <[log in to unmask]> wrote: > Dear FSL list, > I have a question that regards both fslvbm and sienax. I have two populations one patient and the other control. I performed fslvbm on both groups and then did randomise to find group differences. I was wondering is it possible to limit the sienax normalized calculations to only the significant regions that were revealed from the fslvbm? In other words I binarized the fslvbm results and I only want to include those voxels instead of the entire brain. > > Thank you, > Jeremy >