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Hi Jon, our Cochrane review on neuraminidase inhibitors has only regulatory information, no evidence from publications was included. Best, Tom Sent from my iPhone On 23/ott/2012, at 20:31, "Poses, Roy" <[log in to unmask]> wrote: > And then there is the whole issue of trials that are not published at all because their results do not support the sponsors' interests, and there is at least some evidence that this may distort the results of systematic reviews by Turner et al in the NEJM: > > http://www.nejm.org/doi/full/10.1056/NEJMsa065779 > > On Tue, Oct 23, 2012 at 1:53 PM, Jon Brassey <[log in to unmask]> wrote: >> Hi Ahmed, >> >> I'm more interested in the 2) question. I appreciate that any studies found in systematic reviews are not in medline (and/or PubMed) but - in reality, does it make a huge amount of difference? The reference found by Julie (http://www.hta.ac.uk/project/1099.asp) suggests (and I've only based this on the summary) that it doesn't make a big difference. They state: >> >> Systematic reviews that are based on a search of English language literature that is accessible in the major bibliographic databases will often produce results that are close to those obtained from reviews based on more comprehensive searches that are free of language restrictions. >> >> I imagine the article will unpick the medline/pubmed versus other 'major bibliographic databases' but I may be disappointed. >> >> BW >> >> jon >> >> >> >> On Tue, Oct 23, 2012 at 6:39 PM, Ahmed Abou-Setta, M.D. <[log in to unmask]> wrote: >>> Hi Jon, >>> >>> >>> >>> For clarification, do you mean ‘studies included in PubMed but that are not Medline-indexed’ or do you mean ‘studies found in other databases (e.g. Embase, Central, Cinahl, etc.) but that are not Medline-indexed’? >>> >>> >>> >>> Both questions are valid and in my mind could be: >>> >>> >>> >>> 1) What is the difference between Medline and Pubmed? >>> >>> 2) Why should be search outside Medline? >>> >>> >>> >>> Ahmed >>> >>> >>> >>> >>> >>> From: Evidence based health (EBH) [mailto:[log in to unmask]] On Behalf Of Jon Brassey >>> Sent: Tuesday, October 23, 2012 12:13 PM >>> To: [log in to unmask] >>> Subject: Medline based systematic review >>> >>> >>> >>> Hi All, >>> >>> >>> >>> I apologise if this turns out to be a stupid question. But can people point me to any systematic review based meta-analysis that has been repeated with all non-Medline articles removed? In other words you're comparing a meta-analysis based on 'all' RCTs versus those just in Medline. >>> >>> >>> >>> Best wishes >>> >>> >>> >>> jon >>> -- >>> >>> Jon Brassey >>> >>> TRIP Database >>> >>> http://www.tripdatabase.com >>> >>> Find evidence fast >>> >> > > > > -- > Roy M. Poses MD FACP > President > Foundation for Integrity and Responsibility in Medicine (FIRM) > [log in to unmask] > Clinical Associate Professor of Medicine > Alpert Medical School, Brown University > [log in to unmask] >